Sabtu, 22 Februari 2014

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Deadly Medicines and Organised Crime: How Big Pharma Has Corrupted Healthcare, by Peter Gotzsche

PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART DISEASE AND CANCER. In his latest ground-breaking book, Peter C Gotzsche exposes the pharmaceutical industries and their charade of fraudulent behaviour, both in research and marketing where the morally repugnant disregard for human lives is the norm. He convincingly draws close comparisons with the tobacco conglomerates, revealing the extraordinary truth behind efforts to confuse and distract the public and their politicians. The book addresses, in evidence-based detail, an extraordinary system failure caused by widespread crime, corruption, bribery and impotent drug regulation in need of radical reforms. "The main reason we take so many drugs is that drug companies don't sell drugs, they sell lies about drugs. This is what makes drugs so different from anything else in life...Virtually everything we know about drugs is what the companies have chosen to tell us and our doctors...the reason patients trust their medicine is that they extrapolate the trust they have in their doctors into the medicines they prescribe. The patients don't realise that, although their doctors may know a lot about diseases and human physiology and psychology, they know very, very little about drugs that hasn't been carefully concocted and dressed up by the drug industry...If you don't think the system is out of control, please email me and explain why drugs are the third leading cause of death...If such a hugely lethal epidemic had been caused by a new bacterium or a virus, or even one-hundredth of it, we would have done everything we could to get it under control." FROM THE INTRODUCTION

  • Sales Rank: #338974 in Books
  • Published on: 2013-08-28
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.90" h x .60" w x 6.10" l, 1.30 pounds
  • Binding: Paperback
  • 322 pages

About the Author
Professor Peter C Gotzsche graduated as a Master of Science in biology and chemistry in 1974 and as a physician in 1984. He is a specialist in internal medicine; he worked with clinical trials and regulatory affairs in the drug industry 1975-83, and at hospitals in Copenhagen 1984-95. He co- founded The Cochrane Collaboration in 1993 and established The Nordic Cochrane Centre the same year. He became professor of Clinical Research Design and Analysis in 2010 at the University of Copenhagen. Peter Gotzsche has published more than 50 papers in 'the big fi ve' (BMJ, Lancet, JAMA, Annals of Internal Medicine and New England Journal of Medicine) and his scientifi c works have been cited over 10 000 times. Peter Gotzsche has an interest in statistics and research methodology. He is a member of several groups publishing guidelines for good reporting of research and has co- authored CONSORT for randomised trials (www.consort- statement. org), STROBE for observational studies (www.strobe- statement.org), PRISMA for systematic reviews and meta- analyses (www.prisma- statement.org), and SPIRIT for trial protocols (www.spirit- statement.org). Peter Gotzsche is an editor in the Cochrane Methodology Review Group.

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122 of 124 people found the following review helpful.
Big pharma and the Mafia
By Mauricio J. Solorzano
One of the biggest canaries at the moment is Peter Gøtzsche, none other than the head of the Nordic Cochrane Centre, the Scandanavian arm of the Cochrane Collaboration, an independent research and information centre committed to preparing, maintaining, and disseminating reviews of the various treatments of mainstream medicine and examining whether they have adequate evidence of safety and effectiveness. Cochrane was the first group of individuals to champion the notion of`evidence-based' medicine - that is, medicine shouldn't be used unless there's evidence that the stuff works.

Gøtzsche is a guy after my own heart. When asked to speak at a Danish Society for Rheumatology event, called `Collaboration with the drug industry. Is it THAT harmful?' Peter's opening gambit was to highlight the fact that Pfizer, one of the meeting's sponsors, had been fined $2.3 billion in the US for promoting off-label use of four drugs, while Merck, the sponsor the year before, had been responsible for the deaths of thousands due to deceptive information about its arthritis drug.

Gøtzsche's latest book, entitled Deadly Medicines and Organised Crime: How Big Pharma has Corrupted Healthcare' (Radcliffe Publishing Ltd) pulls even fewer punches. The book essentially makes the point that the drugs industry uses virtually every tactic used by the mob to sell its products.

He even quotes a former vice-president of Pfizer as saying, `It is scary how many similarities there are between his industry and the mob. The mob makes obscene amounts of money, as does this industry. The side effects of organized crime are killings and deaths, and the sides effects are the same in this industry. The mob bribes politicians and others, and so does the drug industry.'

Perhaps even more extraordinary than the careful case made by this blunt soothsayer is the fact that Richard Smith, the former editor of the British Medical Journal, agreed to write the book's foreword. In the book, Smith points out, the characteristics of organized crime include extortion, fraud, federal drug offences, bribery, embezzlement, obstruction of justice obstruction of law enforcement, tampering with witnesses and political corruption.

"Peter produces evidence, most of it detailed, to support his case that pharmaceutical companies are guilty of most of these offenses," says Smith. Indeed, most of the billions paid out as fines by the drugs industry for flouting the law as thought of as `the cost of doing business.'

"As an epidemiologist with very high numerical literacy and a passion for details, so that he is a world leader in critiquing clinical studies, Peter is here on very solid ground," says Smith. "He shows too how the industry has bought doctors, academics, journals, professional and patient organizations, university departments, journalists, regulators and politicians. These are the methods of the mob."

This is only the latest canary from among Establishment medicine to blow the whistle on Big Pharma. Marcia Ancell, the editor for two decades at the new England Journal of Medicine, recently published her own book: The Truth About the Drug Companies: How They Deceive Us and What to Do About It.

All of the major medical journals, from the BMJ and the Lancet, to the Journal of the American Medical Association and the New Eng Journal, have revealed the scale of the problem - that correctly prescribed drugs are the fourth leading cause of death, that drug companies massage and make up data.

Medicine should be a gift to us all rather than a money-making scheme for the pharmaceutical industry, as it now largely is.

With that in mind, we suggest that the following be implemented.

An independent funding body should be created to finance all medical trials, whether of drugs, other forms of therapy or alternatives
Doctors should be required to spend one year of their five-year training learning about nutrition, alternative modalities and new possibilities
Drug-company influence should be entirely excluded from medicine, from training colleges and from trips abroad
Doctors should be rewarded for adopting non-drug therapies, thus saving the nation at least one small part of the £160 billion spent every year on drugs by the NHS.
But most of all, we need to open up the entire field of cancer--our understanding of what it is, what causes it and how it could be treated--while taking on board new understandings of the body and the impact upon it of the environment, stress and emotions. As a researcher once commented when asked whether research into alternative healing should continue, "We can't find the answers if we don't keep asking the questions."

We will shortly announce our campaign for freeing medicine from the pharmaceutical industry, so that doctors and patients alike are free to use an entire toolkit of modalities to get and stay well.

30 of 31 people found the following review helpful.
Polemical but powerful expose of the widespread corruption of big Pharma and their unholy influence on medicine and healthcare.
By D. F. Watt
Polemical but powerful expose of the widespread corruption of big Pharma and their unholy influence on medicine and healthcare. You will not see prescription medicines in quite the same way after reading this. Would have wished for a more scientific and less angry/polemical treatment. The data and the facts themselves will make people angry, and less of that from the author might have made for a better sense of an objective treatment.

As a clinician in the healthcare system for 35+ years, I have to validate the author's sense that healthcare, and indeed virtually every aspect of medicine, has been subjected to and distorted by the commercial agendas and almost unlimited greed of big Pharma. In particular, the abuses of the scientific method in relationship to psychotropic medicines are legion, a place where side effects are concealed and minimized (including very serious ones from neuroleptics) while benefits are blown up and exaggerated. You should read this to get the other side of the advertizing you have absorbed about any drug that you might be taking.

It offers a powerful argument that the current system is completely broken, and must be overhauled.

42 of 43 people found the following review helpful.
Bribed doctotors kill 100 000 Americans every year.
By Nils Simonson
After 45 yrs as a doctor I feel cheated.The experts evaluating the drugs are cheating us bribed by Big bad Pharma.Thanks P Goetzsche for opening my eyes.

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  • Sales Rank: #2631069 in Books
  • Published on: 2002
  • Binding: Paperback

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Excellent resource
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Jumat, 21 Februari 2014

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Organic Photochemistry and Pericyclic Reactions, by s Kalaivani

Since the knowledge of Organic reaction mechanism is essential for understanding the course of Organic chemistry, a study of Organic reaction mechanism now forms an essential part of the Organic chemistry courses in all the Universities. This book is intended for students at the graduate and postgraduate level. Due to wide coverage and simple style, students at all levels can get benefited from this book All topics have been selected with great care keeping in mind the needs of the students. Certain topics which are generally discussed in introductory books are excluded. Each chapter concludes with a set of review questions.

  • Sales Rank: #3097617 in Books
  • Published on: 2013-07-02
  • Original language: English
  • Dimensions: 9.69" h x .36" w x 7.44" l,
  • Binding: Paperback
  • 156 pages

About the Author
S.Kalaivani has got 16 years of experience in teaching Organic Chemistry for both UG and PG at AVC College, Mannampandal, Mayiladuthurai, Tamilnadu.She completed her UG at Madras University,PG and M.Phil at Bharathidasan University and B.Ed at Annamalai University and now pursuing her doctral studies. Her field of research is Semiconductor Photocatalysis and her area of interest is Organic Chemistry.

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About Face: The Odyssey of an American Warrior, by Colonel David H. Hackworth, Julie Sherman

Called “everything a twentieth century war memoir could possibly be” by The New York Times, this national bestseller by Colonel David H. Hackworth presents a vivid and powerful portrait of a life of patriotism.

From age fifteen to forty David Hackworth devoted himself to the US Army and fast became a living legend. In 1971, however, he appeared on television to decry the doomed war effort in Vietnam. With About Face, he has written what many Vietnam veterans have called the most important book of their generation.

From Korea to Berlin, from the Cuban missile crisis to Vietnam, Hackworth’s story is that of an exemplary patriot, played out against the backdrop of the changing fortunes of America and the American military. It is also a stunning indictment of the Pentagon’s fundamental misunderstanding of the Vietnam conflict and of the bureaucracy of self-interest that fueled the war.

  • Sales Rank: #12818 in Books
  • Brand: Touchstone
  • Published on: 1990-04-15
  • Released on: 1990-04-15
  • Ingredients: Example Ingredients
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.25" h x 2.10" w x 6.12" l, 2.74 pounds
  • Binding: Paperback
  • 875 pages
Features
  • Great product!

About the Author
David H. Hackworth (Col., U.S. Army, Ret.) spent almost five years of combat duty in Vietnam, as well as twenty-five years in the service of our nation's defense. His previous two nonfiction books, About Face (available from Touchstone) and Hazardous Duty, and his novel, The Price of Honor,The Price of Honor, were national bestsellers. Eilhys England produces feature films and writes with her partner and husband, David Hackworth. They live in Connecticut and Australia.

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69 of 71 people found the following review helpful.
Vietnam - a defining point of his life
By Michael Horn
[Sadly for all of us, Col David Hackworth died shortly after I wrote this review. Nothing about him or my review of his works needs revision. Hack - we will miss you! Hack - RIP, Mike H, LTC, MI, USA 1970-1996].

Say what you want about Hackworth - you can't deny him his valor or experiences in the Army. "Hack" continues to thrive on controversy - one who is not afraid to stir the pot. This book was his first view on the public stage after his Vietnam exit from the Army.

As a young officer - I first read this book in the career stage of my commission - as a Major - and came away with mixed feelings about his views and attitudes. Hackworth's Vietnam experience - like that of John Kerry's, was a defining point of his life. Both came away from that service determined to change the way government uses the military. Kerry became an anti-military cynic; Hackworth lashed out at the systems' waste and stupidity - in an attempt to make the system better.

During war, Hack would be a leader one would wish to serve under. In peacetime - like so many other warriors - he'd be a disaster in the mindless training environment of a peacetime army. Like a fire extinguisher - keep under glass until an emergency demands his use.

The book is deliberately written to stir controversy. This IS Hackworth and what he is all about. Step on a few important toes to save good soldiers - this IS and always was his intent. When he drifts to politics - watch out! He has no friends in either political party.

If you have never served - and are thinking of signing up - maybe this will give you pause. If the world awaits you as a grand adventure - do what he did - and wear the uniform proudly for a majority of your adult life. At the least - Hackworth made me stop and think along the way. My latter years in uniform were constant battles against mind numbing stupidity and for care and protection of our countries' most valuable assets - the men and women who served under my leadership. I have learned much from this soldier. Buy and read the book. You will come away a changed person.

50 of 54 people found the following review helpful.
A born warrior
By Jon R. Schlueter
A juvenile delinquent, Hackworth, flees from his confinement and joins the Merchant Marine. Later, he pays off a wino to sign a fraudulent affidavit, as Hackworth's "father" (he was an orphan), that allows him to enter the Army at the age of fifteen. This is the beginning of this book, which ends with this man, now a Colonel, venting condemnation of America's tactics in Vietnam in the press, and his subsequent persecution by Army investigators, in a harrowing, white-knuckle ending.
A man is lucky to find his calling, and Hackworth was born to be a warrior. In a way, this book is an inspiration. It makes one want to be as good in one's profession as Hackworth was in his. And no matter what one's occupation is, one can identify with Hackworth's frustration with and anger at the "perfumed princes" who rose to the top in the Army he knew, and whos' equivalents exist in every field of endeavor. Don't you know people who don't give a grape-skin about the higher goals of their profession, and who live only to feed their ambition? Reading this book is like sitting down and listening to somebody who knows the score.

22 of 22 people found the following review helpful.
Inspiring and Educational, yet Worrying
By A Customer
Two main themes came out of "About Face" for me. The first is that it is an excellent "how-to" manual on practical leadership in the military. All of the lessons pounded into me as an Officer Cadet are shown here. Know you soldiers, care for them, lead by example, don't get them to do what you wouldn't..., the list goes on. In my opinion, this book, or at least large parts of it, should be required reading in every Officer training establishment that seeks to produce real commanders. As I read it, lights came on in my head as I began to understand some of the points I had missed in my training as a cadet. I believe it has been of some benefit to my performance as an Army Officer. For any cadets or junior officers out there, read this book.
The second theme is the way in which he describes an Army sinking into the morass so common of militaries in peacetime. The most worrying thing for me was the parallels I could see happening in my own Army. An easing of standards in recruitment and basic training, decisions being made based on politics and finance, rather than on realities, increasing bureaucratisation and micromanagement, etc, etc, etc. Things seem to be the same all over. Unfortunately, neither Col Hackworth nor I can give any easy answers.
Overall, an excellent book,that should provoke a few thoughts.

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Jumat, 07 Februari 2014

[Z357.Ebook] Free PDF Structural Design for Physical Security: State of the Practice, by Ted Krauthammer, Kirk A. Marchand, Paul F. Mlakar

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Structural Design for Physical Security: State of the Practice, by Ted Krauthammer, Kirk A. Marchand, Paul F. Mlakar

Structural Design for Physical Security: State of the Practice, by Ted Krauthammer, Kirk A. Marchand, Paul F. Mlakar



Structural Design for Physical Security: State of the Practice, by Ted Krauthammer, Kirk A. Marchand, Paul F. Mlakar

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Structural Design for Physical Security: State of the Practice, by Ted Krauthammer, Kirk A. Marchand, Paul F. Mlakar

As dramatized by the bombing of the World Trade Center in New York City and the Murrah Building in Oklahoma City, civil engineers today need guidance on how to design structures to resist various hostile acts. While the U.S. military services and U.S. foreign embassy facilities both have developed their unique requirements, the documents are restricted to official use only. No widely available document has existed to provide engineers the technical data necessary to design civil structures for enhanced physical security. In recognition of this void, the ASCE created a Task Committee to produce this "State of the Practice Report", which provides guidance to structural engineers in the design of civil structures to resist the effects of terrorist bombings. This report includes unrestricted government information, which is for the first time assembled collectively and rephrased for application to civilian facilities. Eight chapters outline the steps commonly followed in this practice. These are the determination of the threat, methods by which structural loadings are derived for the determined threat, the behavior and selection of structural systems, the design of structural components, the design of security doors, the design of utility openings, and the retrofitting of existing structures. This report is the first transfer of this technology to the civil sector, and provides complete methods, guidance, and references for structural engineers challenged with a physical security problem.

  • Sales Rank: #2243084 in Books
  • Published on: 1999-10
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.25" h x 5.50" w x .75" l, .65 pounds
  • Binding: Paperback
  • 264 pages

Most helpful customer reviews

1 of 1 people found the following review helpful.
Title mis stated.
By Jay Peterson
It is more of a philosophy than a technical book, there are no mathematical design examples given. Design should have been left out of the title.

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